Notre Dame Regional High School

Cape Girardeau, MO

seal background


Welcome to NDRHS!

Enter to Learn, Leave to Serve

Notre Dame Regional High School, located in Cape Girardeau, Missouri, is comprised of students in grades 9 through 12. We are recognized as an Ambassador school by the Catholic High School Honor Roll. Our students travel up to 60 miles one-way from several communities in Southeast Missouri and Southern Illinois to attend Notre Dame. Notre Dame serves as host to several international students, including former students from Japan, China, Indonesia, South Korea, Thailand, Mexico, Spain, Brazil, and Germany.



Below you will find the application process for enrollment at Notre Dame Regional High School. 

Incoming Freshman

Students in eighth grade who are interested in attending Notre Dame in the fall of their ninth grade year should plan to attend our Open House in November and take our Placement Test in January.  Below you will find a snapshot of important event months as well as a more detailed Parent Checklist.  Please check our School Calendar for specific event dates.

Parent Checklist

Tips for Registering Online

November - Open House
January - Placement Test
Late February/early March - Registration


Current Student Re-Enrollment

Parent Checklist

Re-Enrollment begins in January.


  • Online under Parent's PlusPortals - choose FORMS in the dark blue bar at the top.
  • Choose View/Edit to complete.
  • Enter any additions or changes to the form and also provide Medical Consent on the last page (the checkbox is at the bottom).
  • You may choose to pay your registration online or if you prefer, click on Pay by Mail (once you hit Pay and Submit - there is a Pay By Mail check box to the right of the credit-card entry information) and either mail or send a check with your student. Registration for 2020-2021 is $125.


Course Selection Forms (color forms with class selections)

  • Students get required teacher signatures on the paper form.
  • Students are also required to complete the electronic version in the Student's PlusPortals.


Transfer Student

Students who are interested in transferring to our school during or after their ninth grade year must make an appointment with the Guidance office by calling 573-335-3701.

Please review the information below:

Parent Checklist


You will need:

New Student Application

Consent for Release of Information Form

Registration Form


International Student

Notre Dame Regional High School partners with Three W International to provide comprehensive international student enrollment management to students from China. Together, we are able to provide unparalleled support and service to our international students, from general admissions to post-arrival and beyond. If you are a student from China and are interested in applying to Notre Dame Regional High School, please contact Three W International.

Students from Other Countries

If you are a student from another country interested in attending Notre Dame Regional High School, please contact our Guidance Department at: +1 573-335-3701 ext. 1, for more information.

Interested in Becoming a Host Family?

Rebecca Sellers
Area Manager
Office: (424) 239-6367
Mobile: (510) 993-4140




NDHS Alum Meghan Dohogne Highlighted at UMKC


Meet Our Alumni: William Lindman '05


Meet Our Alumni: Ryan Eftink '95


Meet Our Alumni: Jessie Ritter '11


Onto Harvard: 2011 Graduate Mary Katherine Montgomery Works To Intertwine Health And Education Systems


Congratulations Class of 2019


Bulldogs at Busch Win


ND Graduate Returns to Share Experience


Graduate participates in Mission Trip


Athletic Hall Of Fame: 2009 Graduate John Unterreiner